Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group
نویسندگان
چکیده
منابع مشابه
Cortical GABA in Subjects at Ultra-High Risk of Psychosis: Relationship to Negative Prodromal Symptoms
Background Whilst robust preclinical and postmortem evidence suggests that altered GABAergic function is central to the development of psychosis, little is known about whether it is altered in subjects at ultra-high risk of psychosis, or its relationship to prodromal symptoms. Methods Twenty-one antipsychotic naïve ultra-high risk individuals and 20 healthy volunteers underwent proton magneti...
متن کاملRisk factors for psychosis in an ultra high-risk group: psychopathology and clinical features.
The identification of individuals at high risk of developing a psychotic disorder has long been a goal of clinicians because it is thought that early treatment of this group may prevent onset of the disorder. However, little is known of predictive factors of psychosis, even within a high-risk group. This study followed up 104 young people thought to be at 'ultra high risk' for schizophrenia and...
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BACKGROUND While deficits in cognitive functions are frequently reported in psychotic disorders, further longitudinal research is needed to confirm the specific risk factors for the development of psychosis. We examined longitudinally the social-cognitive and neurocognitive function of individuals at ultra-high risk for schizophrenia who developed psychosis later as predictive markers. METHOD...
متن کاملChildhood trauma and clinical outcome in patients at ultra-high risk of transition to psychosis.
BACKGROUND Although transition rates in 'ultra-high risk' (UHR) for psychosis samples are declining, many young individuals at UHR still experience attenuated positive symptoms and impaired functioning at follow-up. The present study examined the association between a history of childhood trauma and transition to psychosis, and symptomatic and functional outcome, in UHR patients. METHOD Data ...
متن کاملCircadian rhythm disturbances and conversion to psychosis in ultra high-risk youth.
tolerance since the start of treatment. Nefopam was also introduced for the management of hemorrhoid pain as needed, at 20 mg/d (po). After an additional 35 days of treatment with clozapine at 350 mg/d, one night the patient had hematemesis and diffuse abdominal pain. The next morning, she experienced vomiting and complained of epigastric pain. The patient was treated with domperidone (30 mg/d)...
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ژورنال
عنوان ژورنال: Acta Psychiatrica Scandinavica
سال: 2010
ISSN: 0001-690X,1600-0447
DOI: 10.1111/j.1600-0447.2010.01542.x